Binding and modification of proteins by methylglyoxal under physiological conditions. A kinetic and mechanistic study with N alpha-acetylarginine, N alpha-acetylcysteine, and N alpha-acetyllysine, and bovine serum albumin.
نویسندگان
چکیده
منابع مشابه
Binding and Modification of Proteins by Methylglyoxal under Physiological Conditions
The physiological a-oxoaldehyde methylglyoxal binds and modifies arginine, lysine, and cysteine residues in proteins. The kinetics and mechanism of these reactions were investigated with Na-acetylamino acids and bovine serum albumin at pH 7.4 and 37 “C. The reaction of methylglyoxal with Na-acetylarginine involved the initial reversible formation of glycosylamine and 4,5-dihydroxy5-methylimidaz...
متن کاملDynamics of higher order rational difference equation $x_{n+1}=(alpha+beta x_{n})/(A + Bx_{n}+ Cx_{n-k})$
The main goal of this paper is to investigate the periodic character, invariant intervals, oscillation and global stability and other new results of all positive solutions of the equation$$x_{n+1}=frac{alpha+beta x_{n}}{A + Bx_{n}+ Cx_{n-k}},~~ n=0,1,2,ldots,$$where the parameters $alpha$, $beta$, $A$, $B$ and $C$ are positive, and the initial conditions $x_{-k},x_{-k+1},ldots,x_{-1},x_{0}$ are...
متن کاملa comparative study of language learning strategies employmed by bilinguals and monolinguals with reference to attitudes and motivation
هدف از این تحقیق بررسی برخی عوامل ادراکی واحساسی یعنی استفاده از شیوه های یادگیری زبان ، انگیزه ها ونگرش نسبت به زبان انگلیسی در رابطه با زمینه زبانی زبان آموزان می باشد. هدف بررسی این نکته بود که آیا اختلافی چشمگیر میان زبان آموزان دو زبانه و تک زبانه در میزان استفاده از شیوه های یادگیری زبان ، انگیزه ها نگرش و سطح مهارت زبانی وجود دارد. همچنین سعی شد تا بهترین و موثرترین عوامل پیش بینی کننده ...
15 صفحه اولpostnatal studies of bats (pipistrellus kuhlii and miniopterus schreibersii) & histomorphology and histochemistry studies of organs and diseases of (neurergus microspilotus and n. kaiseri)
1. to determine whether difference in birth body mass influenced growth performance in pipistrellus kuhlii we studied a total of 12 captive-born neonates. bats were assigned to two body mass groups: light birth body mass (lbw: 0.89 ± 0.05, n=8) and heavy birth body mass (hbw: 1.35 ± 0.08, n=4). heavier body mass at birth was associated with rapid postnatal growth (body mass and forearm length) ...
a comparison of teachers and supervisors, with respect to teacher efficacy and reflection
supervisors play an undeniable role in training teachers, before starting their professional experience by preparing them, at the initial years of their teaching by checking their work within the proper framework, and later on during their teaching by assessing their progress. but surprisingly, exploring their attributes, professional demands, and qualifications has remained a neglected theme i...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1994
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)31635-1